Yes, the conversion wizard in Visual Studio 2010 damages several *.Designer.cs files, which introduces build errors. I've described the problem at
http://nodexl.codeplex.com/releases/view/96393, and I'll include the description and workaround here, below my signature.
I will eventually convert the solution to Visual Studio 2012, bypassing 2010 entirely.
To use the NodeXL source code in Visual Studio 2010, do the following:
1. Download the source code from the Source Code tab.
2. Make copies of the original NodeXL\ExcelTemplate\*.Designer.cs files. There are eight of them: Sheet1.Designer.cs, Sheet2,Designer.cs, and so on.
3. Make a copy of the original NodeXL\ExcelTemplate\GraphMetrics\GraphMetricDescriptions.Designer.cs file.
4. Open NodeXL.sln in Visual Studio 2010, which starts the conversion wizard.
5. Let the conversion wizard run to completion. The conversion succeeds without complaint, but unfortunately the *.Designer.cs files get mangled during the conversion.
6. Overwrite the (badly converted) *.Designer.cs files with the copies you made earlier.
7. See NodeXL\HowToBuildNodeXL.txt.